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Going crazy or thyroid issues?

2089 Views 3 Replies 3 Participants Last post by  akimbo, 
A
Am one step away from divorce, due to my being "withdrawn and unloving". I've been off and (mostly) on 25 mg of Synthroid for about 7 years. My blood work has always been 'normal' but I was put on medication for inability to concentrate. I ran out about 3 weeks ago, but two weeks ago saw my g.p. to talk to her about whether I need synthroid at all. She sent me for blood work which came back normal, but then said the test was actually a waste of time because I would need to be off the med for a month to see if I'm able to produce my own thyroxin. Gee thanks for that.

Have fibromyalgia, small-fiber neuropathy, tinnitus, depression, lots of chemical sensitivities and lately: chronic insomnia, increasing memory loss and some panicky thoughts of claustrophobia. Since going off synthroid 3 weeks ago, it seems like a different sweating patterm than menopause. At the same time, I've needed my electric blanket on a few evenings for chills. Have had no interest in sex for several years and my husband's patience is running out. I couldn't even fake interest if my life depended on it, but occassionally, I give in for his sake. There is growing resentment on both sides. Appart from that we have good things in our life, including a nice house, good friends, and a great dog, and we respect each other's achievements and knowledge. I do feel bad that my husband isn't getting what he needs. Mostly he's tolerant, and not a chauvenist but there is a seething undercurrent of resentment about my being 'distant' and occassionally, like this morning, a huge argument. I don't know how much the thyroid is at play in all this. I feel a lot of confusion and sadly, my doctor is not helpful. The endocrinologist I saw 2 years ago was not helpful either. She said none of the tests were difinitive for thyroid problem. Does this sound like it's thyroid related?

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Andros
SUGGESTED TESTS
TPO (antimicrosomal antibodies) TBII (thyrotropin-binding inhibitory immunoglobulin), Thyroglobulin and Thyroglobulin Ab, ANA (antinuclear antibodies), (thyroid hormone panel) TSH, Free T3, Free T4.

You can look this stuff up here and more.........
http://www.labtestsonline.org/
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TBII
http://www.ncbi.nlm.nih.gov/pubmed/9364248
http://en.wikipedia.org/wiki/Anti-thyroid_autoantibodies
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Blocking TRAbs (also known as Thyrotropin Binding Inhibitory Immunoglobulins (TBII)) competitively block the activity of TSH on the receptor. This can cause hypothyroidism by reducing the thyrotropic effects of TSH. They are found in Hashimoto's thyroiditis and Graves' disease and may be cause of fluctuation of thyroid function in the latter. During treatment of Graves' disease they may also become the predominant antibody, which can cause hypothyroidism.

TSI
Normally, there is no TSI in the blood. If TSI is found in the blood, this indicates that the thyroid stimulating immunoglobulin is the cause of the of a person's hyperthyroidism.
http://labtestsonline.org/understanding/analytes/thyroid-antibodies/tab/test
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Understanding the Thyroid: Why You Should Check Your Free T3
http://breakingmuscle.com/
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Dr. Mercola (FREES)
http://www.mercola.com/article/hypothyroid/diagnosis_comp.htm

Free T3 and Free T4 are the only accurate measurement of the actual active thyroid hormone levels in the body. This is the hormone that is actually free and exerting effect on the cells. These are the thyroid hormones that count.

Substances not found in normal serum (scroll down to autoantibodies)
http://www.thyroidmanager.org/chapter/evaluation-of-thyroid-function-in-health-and-disease/
(Copy and paste into your browser)

Welcome to the board!

Why are not the ranges included on that thumbnail? Does the lab not provide them?

You do have thyroid issues as evidenced by the presence of the antibodies and the extreme fluctuation of the TSH over the year.

You do need a new doctor; definitely and you must insist on an ultrasound of your thyroid as the high antibodies demand that that course of action be taken.

And I am listing info for you which I do hope you read.

This is a sin; I am sorry for your situation and that your illness has been dismissed by your doctor.
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Octavia
Let's assume for a moment that you DO need the Synthroid. It's pretty rare that 25 mcg is enough to make a difference. It's really hard to tell without your lab's ranges.

Now, let's assume for a moment that you DON'T need the Synthroid. What else has your doctor explored with you? Have you talked at length with your doctor about the lack of interest in sex? What have you tried in your efforts to improve your libido? Any sex hormones?
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A
Octavia said:
Let's assume for a moment that you DO need the Synthroid. It's pretty rare that 25 mcg is enough to make a difference. It's really hard to tell without your lab's ranges.

Now, let's assume for a moment that you DON'T need the Synthroid. What else has your doctor explored with you? Have you talked at length with your doctor about the lack of interest in sex? What have you tried in your efforts to improve your libido? Any sex hormones?
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Thanks Super Moderator + Administrator. I live in a small town and, for various reasons, am stuck with this young doctor. No I haven't talked to her about lack of interest in sex. I was on DHEA for several years, which was controversial, but that didn't make any difference. I actually feel some relief that the sex thing is over. :) Too bad for hubby. As of today, I'm back on synthroid. Thanks for listening in my 'hour of need.' I clearly need to learn more about this medication.
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