Quick update, I'm now almost 3 months after my total thyroidectomy and I'm having lots of issues getting regulated on medication. Just had new labs done today, TSH, free T4 and free T3. My endo has been working to get my dose correct but whatever we do, I get symptomatic, sometimes hyper and sometimes hypo symptoms. My current dose is Synthroid 75 mcg and cytomel 2.5 mg twice daily. How long should it take to find the right dose? Any insight would help, I'm getting so depressed and spending too much time not feeling functional. Thank heavens for supportive family and coworkers tho!