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Hello, I am pretty new at all the thyroid test and such. I recently really started researching different tests and thyroid disorders, I have had the basic TSH test done MANY times in my life. It has always come back as they say "normal". I never questioned that because the doctors and labs know best right???? This is what I always thought......now not so much. At my last visit I asked why they dont do a diiferent test on me. She said they dont do this unless TSH is off. Well now I am going to insist that they do ALL testing available. I am mad as hell!

I have had so many symptoms for so may years and for them not to test me is wrong on there part! My symptoms first were mainly extreme fatigue...depression and very hard to lose weight. I even had weighloss surgery (lapband) since been removed because I stopped losing weight even with that.

New symptoms are feeling like a lump in my throat......impossible to lose weight even with exercise....my mind is gone (brain fog) impossible to concentrate & very forgetful...depression....achy body....MOOD swings.....heavy very painful periods,,,.anxiety.... ect ect ect..... My MOTHER also has Graves disease.

Sometimes I feel like I go back and forth from hypo to hyper. Is this possible?

I have been diagnosed with depression, ADD, possible bipolar...have been tested for RA, told possible fybro, diagnosed with reflux (feeling of lump in throat). So, I am at my wits end......if all these thyroid test come back normal I dont know what to do next. I know there is something going on with my body thata is not right. Sometimes I feel like I am crazy or feel like a hypocondriact. I suffer in silents because I feel people think i am making it all up. Thank you for your help in advance.
 

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It's very likely you have an autoimmune condition, especially with that family history, and very likely you are swinging from hypo to hyper and back again.

That all said, it's hard to give out any advice without seeing some labs (which, yes, I realize your doctor doesn't want to run). Do you, minimally, have your TSH results? Are you able to switch doctors?
 

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TSI
Normally, there is no TSI in the blood. If TSI is found in the blood, this indicates that the thyroid stimulating immunoglobulin is the cause of the of a person's hyperthyroidism.
http://labtestsonline.org/understanding/analytes/thyroid-antibodies/tab/test
(Copy and paste into your browser)

Trab
http://www.ncbi.nlm.nih.gov/pubmed/17684583
(Copy and paste into your browser)

Blocking TRAbs (also known as Thyrotropin Binding Inhibitory Immunoglobulins (TBII)) competitively block the activity of TSH on the receptor. This can cause hypothyroidism by reducing the thyrotropic effects of TSH. They are found in Hashimoto's thyroiditis and Graves' disease and may be cause of fluctuation of thyroid function in the latter. During treatment of Graves' disease they may also become the predominant antibody, which can cause hypothyroidism.

TPO Ab
Mild to moderately elevated levels of thyroid antibodies may be found in a variety of thyroid and autoimmune disorders, such as thyroid cancer, Type 1 diabetes, rheumatoid arthritis, pernicious anemia, and autoimmune collagen vascular diseases. Significantly increased concentrations most frequently indicate thyroid autoimmune diseases such as Hashimoto thyroiditis and Graves disease.
http://labtestsonline.org/understanding/analytes/thyroid-antibodies/tab/test
(Copy and paste into your browser)

Substances not found in normal serum (scroll down to autoantibodies)
http://www.thyroidmanager.org/chapter/evaluation-of-thyroid-function-in-health-and-disease/
(Copy and paste into your browser)

TPO (antimicrosomal antibodies) TBII (thyrotropin-binding inhibitory immunoglobulin), Thyroglobulin Ab, ANA (antinuclear antibodies), (thyroid hormone panel) TSH, Free T3, Free T4.

You can look this stuff up here and more.........
http://www.labtestsonline.org/
(Copy and paste into your browser)

You can look the other stuff in the labstest link.

Welcome!

Yes; relying on TSH only eventually leads to trouble as there are antibodies that attack the TSH receptor sites and give a false reading.

Hopefully, you will find a doctor to run TSH, FREE T4 and FREE T3. Also, TPO, Thyroglobulin Ab and Trab. I will furnish links.

Ultra-scan of the thyroid would be a good thing also.

Make sure you get the FREES, not the Totals on the 3 & 4 hormone tests.
 

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Discussion Starter · #5 ·
It's very likely you have an autoimmune condition, especially with that family history, and very likely you are swinging from hypo to hyper and back again.

That all said, it's hard to give out any advice without seeing some labs (which, yes, I realize your doctor doesn't want to run). Do you, minimally, have your TSH results? Are you able to switch doctors?
I am seeing my RA doc tomorrow for a follow up. I hear he is very good with listening and trying different tests and such....so we shall see. I am going to request all of my lab results from the past from my PC as well so i can have them on file. TY.
 

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Discussion Starter · #6 ·
TSI
Normally, there is no TSI in the blood. If TSI is found in the blood, this indicates that the thyroid stimulating immunoglobulin is the cause of the of a person's hyperthyroidism.
http://labtestsonline.org/understanding/analytes/thyroid-antibodies/tab/test
(Copy and paste into your browser)

Trab
http://www.ncbi.nlm.nih.gov/pubmed/17684583
(Copy and paste into your browser)

Blocking TRAbs (also known as Thyrotropin Binding Inhibitory Immunoglobulins (TBII)) competitively block the activity of TSH on the receptor. This can cause hypothyroidism by reducing the thyrotropic effects of TSH. They are found in Hashimoto's thyroiditis and Graves' disease and may be cause of fluctuation of thyroid function in the latter. During treatment of Graves' disease they may also become the predominant antibody, which can cause hypothyroidism.

TPO Ab
Mild to moderately elevated levels of thyroid antibodies may be found in a variety of thyroid and autoimmune disorders, such as thyroid cancer, Type 1 diabetes, rheumatoid arthritis, pernicious anemia, and autoimmune collagen vascular diseases. Significantly increased concentrations most frequently indicate thyroid autoimmune diseases such as Hashimoto thyroiditis and Graves disease.
http://labtestsonline.org/understanding/analytes/thyroid-antibodies/tab/test
(Copy and paste into your browser)

Substances not found in normal serum (scroll down to autoantibodies)
http://www.thyroidmanager.org/chapter/evaluation-of-thyroid-function-in-health-and-disease/
(Copy and paste into your browser)

TPO (antimicrosomal antibodies) TBII (thyrotropin-binding inhibitory immunoglobulin), Thyroglobulin Ab, ANA (antinuclear antibodies), (thyroid hormone panel) TSH, Free T3, Free T4.

You can look this stuff up here and more.........
http://www.labtestsonline.org/
(Copy and paste into your browser)

You can look the other stuff in the labstest link.

Welcome!

Yes; relying on TSH only eventually leads to trouble as there are antibodies that attack the TSH receptor sites and give a false reading.

Hopefully, you will find a doctor to run TSH, FREE T4 and FREE T3. Also, TPO, Thyroglobulin Ab and Trab. I will furnish links.

Ultra-scan of the thyroid would be a good thing also.

Make sure you get the FREES, not the Totals on the 3 & 4 hormone tests.
Hi! When u say "Make sure you get the FREES, not the Totals on the 3 & 4 hormone tests." do u mean get those specific tests not just T3 & T4? I am preparing for appointment tomorrow, writing down all symptoms and test I would like him to run. I hope I have better luck with RA doc than I have had with PC. They just keep doing same labs and sending me away.

My biggest fear is that all these labs will be normal. I feel like this is it......I dont know what else to check if these are normal. I am convinced that something is really "off" in my body.

I can totally relate to all the symptoms os Hashimoto's. Thanku for your help. BTW, there is a great face book page about thyroid disease i found......may i share it?
 

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There are TOTAL t3 and TOTAL t4 tests and FREE t3 and FREE t4 tests -- you want the free t3 and free t4 tests....total doesn't help all that much. :)
 

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Discussion Starter · #9 ·
Big let down today.....doctor cancelled because of emergency. I was really upset because I thought I would be on my way to getting some answers with the right tests. Rescheduled for tues. I know thats only a few days but I have been going through this for so long and my symptoms are getting worse. I'm sure meny of u can relate

:-(

Yesterday I felt like my body was racing and I was hot The about 3pm I crashed. Achy all over like I had the flu with chills. I couldnt go to bed untill 2am! even after taking pain med and motrin my legs still ached.
 

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Discussion Starter · #10 ·
Going to see ENT today fro follow up on Scan I had on sinus. Never thought to mention my tight throat/lump in throat to him before because I was going for my sinus. I am going to really push it today and tell him of all my thyroid symptoms and how my doc will only keep running TSH on me. Maybe he can help me! Feeling hopeful! :)
 

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Discussion Starter · #12 ·
Understanding the Thyroid: Why You Should Check Your Free T3
http://breakingmuscle.com/health-medicine/understanding-thyroid-why-you-should-check-your-free-t3
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http://www.stopthethyroidmadness.com/free-t3/
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That is correct; get the FREE T4 and FREE T3.

Info above.

Please let us know how you fare tomorrow. I do hope you are pleased w/your appt..
Hi. Today did not go so well. I told ENT about throat tightening and feeling of lump. He took a look with scope and saw signs of reflux. He basicly didnt even listen to my LONG endless list of thyroid symptoms after he saw signs of reflux. I pushed it and he said he woud run TSH even though I told him it always comes back normal. I question getting false neg with TSH only. he said "well no test is perfect". WTH?!!?!? So, I have to suffer longer because he doesnt want to add on a fw test! Why are doctors so resistant when it comes to this!??!?!? He is ordering an ultra sound! I cant believe he will order an ultra sound but not blood! Makes NO sense. I have app to see RA doc tues and PC thurs. If I can not get them to do the rightt tests i will be paying to get my own done. I saw the links u gave on another persons post. TY!
 
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